Random Analytica

Random thoughts, charts, infographics & analysis. Not in that order

Random Analytica: AstraZeneca COVID-19 vaccine and cases of Thrombosis with thrombocytopenia syndrome (TTS) by Age Group as at 4 July 2021

The Therapeutic Goods Administration (TGA) has updated its latest safety report with one new confirmed death announced. Via the TGA. COVID-19 vaccine weekly safety report – 08-07-2021. Summary:

  • The most frequently reported suspected side effects (link is external) associated with Comirnaty (Pfizer) and AstraZeneca COVID-19 vaccines continue to be events that were seen in the clinical trials, and are commonly experienced with vaccines generally.
  • An external Vaccine Safety Investigation Group (VSIG), convened by the TGA on 2 July 2021, concluded that a very rare but fatal case of immune thrombocytopenia (ITP) in a 61-year-old woman who had received the AstraZeneca vaccine was likely to be related to immunisation.
  • Seven additional cases of blood clots with low blood platelets have been assessed as thrombosis with thrombocytopenia syndrome (TTS) likely to be linked to the AstraZeneca vaccine. When assessed using the United Kingdom (UK) case definition, three were confirmed TTS and four were deemed probable TTS. This brings the total number of cases of TTS to 76 out of five million doses to date.

Simplistically put and based on the above figures you are likely to have an adverse reaction in every approx. 65,000 doses and a fatal reaction in approx. every 1.6-million doses.

To date there have been three deaths linked to the AstraZeneca vaccine. The latest reported fatality via the Australian Broadcasting Corporation. Death of 61-year-old WA woman last month likely linked to AstraZeneca vaccine. Excerpt:

Health authorities have concluded the death of a 61-year-old woman in hospital last month was likely linked to the AstraZeneca COVID-19 vaccine. The West Australian woman received the vaccine in early June and was admitted to Royal Perth Hospital later that month, where she died of a blood disorder.

The federal government’s Therapeutic Goods Administration (TGA) investigated the woman’s death, with an external vaccine safety investigation group of experts deeming the vaccination the likely cause. It based that conclusion on a strong lack of evidence for other causes and the timeframe within which she died after taking the vaccine.

Random Analytica: AstraZeneca COVID-19 vaccine and cases of Thrombosis with thrombocytopenia syndrome (TTS) by Age Group as at 27 June 2021

The Therapeutic Goods Administration (TGA) has updated its latest safety report with no new confirmed deaths reported. Via the TGA. COVID-19 vaccine weekly safety report – 01-07-2021. Summary:

  • The most frequently reported suspected side effects associated with Comirnaty (Pfizer) and AstraZeneca COVID-19 vaccines continue to be events that were seen in the clinical trials, and are commonly experienced with vaccines generally.
  • Five additional cases of blood clots with low blood platelets have been assessed as thrombosis with thrombocytopenia syndrome (TTS) likely to be linked to the AstraZeneca vaccine. When assessed using the United Kingdom (UK) case definition, two were confirmed and three were deemed probable TTS. This brings the total number of cases of TTS to 69.

To date there have been approximately 4.6-million doses of AstraZeneca administered to 30 June (h/t CovidBaseAU) and two confirmed TTS deaths linked to the AstraZeneca vaccine.

It’s also worth noting that younger people are volunteering to get the AstraZeneca jab after the Prime Minister’s surprise announcement earlier this week. We should see that data flow through to next weeks report.

25. Mefloquine Dispatches: BUPA, 17th June 2021

It’s taken two years. A mixture of research/tenacity and outright good luck have got me to this point.

I have finally got into the Neurocognitive Program. It had been called the Mending Military Minds Program but in reality it is an attempt to deal with 3rd wave injuries via anti-malarial medications now opened up to other factors like IED’s or percussive injuries.

Outright good luck too. I got into the program because my Psychologist was sharp enough to pick up on an email from Open Arms.

My Open Arms Psychologist is amazing. Open Arms runs the program. I go through the barrier testing with an Open Arms staffer who is great.

Then I get this…

I don’t do private healthcare. I worked in an Operating Theatre for a year. I have witnessed the damage these companies do to hospitals. They are parasites.

At no time was BUPA mentioned throughout the process. To the best of my knowledge BUPA should have nothing to do with this program. If BUPA were running this I wouldn’t have become involved.

Yet they do… Now I’m stuck with another bullshit process and lengthy delays.

Why does BUPA have anything to do with the Neurocognitive Program?

Update (8th July 2021)

Happy to advise that I received an unsolicited follow-up call from Open Arms enquiring about the Neurocognitive Program booking process. They listened to my concerns and will get back to me about a more suitable appointment.

Good result. Thanks Open Arms.

Random Analytica: AstraZeneca COVID-19 vaccine and cases of Thrombosis with thrombocytopenia syndrome (TTS) by Age Group

The Therapeutic Goods Administration (TGA) has updated its latest safety report with no new deaths reported. Via the TGA. COVID-19 vaccine weekly safety report – 24-06-2021. Summary:

  • The most frequently reported suspected side effects associated with Comirnaty (Pfizer) and AstraZeneca COVID-19 vaccines continue to be events that were seen in the clinical trials, and are commonly experienced with vaccines generally.
  • Five additional cases of blood clots with low blood platelets have been assessed as thrombosis with thrombocytopenia syndrome (TTS) likely to be linked to the AstraZeneca vaccine. When assessed using the UK case definition, three were confirmed and two were deemed probable TTS. However, following reassessment of a previously reported case as being unlikely to be TTS, there is only a net increase of four cases. This brings the total number of cases of TTS to 64.
  • We are also monitoring reports of suspected myocarditis and pericarditis following vaccination with Comirnaty and suspected Guillain-Barre Syndrome following vaccination with the AstraZeneca vaccine. No causal association with either vaccine has been established at this stage.

There have been approximately 4.2-million doses of AstraZeneca administered to 21 June (h/t Jack). On 17 June 2021, the Australian Technical Advisory Group on Immunisation (ATAGI) recommended that Pfizer’s Comirnaty vaccine be preferred over the AstraZeneca vaccine for those aged 16–60 years old. To date there have been two TTS deaths linked to the AstraZeneca vaccine meaning you have an approx. 1/2.1-million chance of dying.

Get vaccinated!

Random Analytica: AstraZeneca COVID-19 vaccine and cases of Thrombosis with thrombocytopenia syndrome (TTS) to 13 June 2021

The Therapeutic Goods Administration (TGA) has updated its latest safety report with no new deaths being reported. Via the TGA. COVID-19 vaccine weekly safety report – 17-06-2021. Summary:

  • The most frequently reported suspected side effects associated with Comirnaty (Pfizer) and AstraZeneca COVID-19 vaccines continue to be events that were seen in the clinical trials, and are commonly experienced with vaccines generally.
  • Twelve additional cases of blood clots with low blood platelets have been assessed as thrombosis with thrombocytopenia syndrome (TTS) likely to be linked to the AstraZeneca vaccine. The increase in the number of cases correlates with an increase in the number of doses of AstraZeneca vaccine administered during the reporting period.
  • This brings the total number of confirmed and probable TTS cases in Australia to 60. Seven of the 12 new cases occurred in individuals in aged between 50 and 59 years. When assessed using the United Kingdom (UK) case definition, three cases were confirmed and nine were deemed probable TTS.

No data was available in this report on AstraZeneca vaccines administered (in the previous week 3.3-million doses were confirmed). At the same time the Australian Technical Advisory Group on Immunisation (ATAGI) recommended the age to receive a dose be increased from 50 to 60. To date there have been two TTS deaths linked to the AstraZeneca vaccine.

Random Analytica: AstraZeneca COVID-19 vaccine and cases of Thrombosis with thrombocytopenia syndrome (TTS)

AstraZeneca is in the news this week after the Therapeutic Goods Administration (TGA) reported the death of a 52-woman from New South Wales from thrombosis with thrombocytopenia syndrome (TTS). This is the second fatality linked to the AstraZeneca vaccination roll-out following the death of a 48-year old female in April. As tragic as the deaths are there have been almost 3.3-million doses of AstraZeneca administered (to the 6th June 2021) with just 48-cases of TTS being reported to date. For context it looks like you could expect an adverse reaction resulting in death in 1 in every 1.65-million doses. According to Ian Mackay from Virology Down Under “It’s a real number. A real risk. But a very rare one”.

Random Analytica: From China with Love

I have been blogging for 10-years now. My best year was back in 2014 as I followed the H7N9 outbreak which originated in China. That year I garnered almost 33,000 views of which just 20 came from mainland China. I then took a break from blogging between 2015 – 2018. In late 2019 I started to blog about some of my experiences in the Australian Army. Since then the hits from China have increased from <1% to 16.7% this year while my Hong Kong viewers have disappeared. It is all the more interesting because I only dwell on Twitter (banned in China) and WordPress via social media. I’ve reached out to some experts in the field including Stephen McDonell (via the BBC) who is reporting in Hong Kong tonight from the vigil on the 32nd anniversary of the Tiananmen Square Massacre.

A letter from Dennis ‘Des’ Nilsen, 5th August 1994

A memory…

24. Mefloquine Dispatches: Sausage rolls and the Red Cross, 1st July 1997

February 2019.

I had been doing memory recall exercises for some weeks at this point.

The process consumes me. I’m not really ready for this type of Rapid Exposure. As I sit with my psychologist we do the work and then he spends time ‘bringing me down’. When I do it on my own I go for hours. I’m a student who thinks he is a professor.

I’m merging into an old pattern which I am starting to recognise. It’s my roller-coaster. Every six to nine months. For more than two decades.

The memory work has been fruitful. I’ve remembered taking the mefloquine which was the SOP (Standard Operating Procedure) at the time. Is that enough to prove I was given mefloquine?

One of the boys gives me a doctor in the United States who I can talk to. I approach him with the evidence I have. He advises that it isn’t enough. I have no notation of mefloquine on my medical records. In fact he noted that I was cleared for doxycycline.

I’m devastated. It doesn’t matter what I can remember or what the SOP was at the time, without some sort of concrete evidence I know I’ll have a hard time proving my exposure.

I do more memory work. I should be resting. I look terrible. I feel awful. I’m not sleeping.

I get a memory.

Sausage rolls! I’m sitting in a clinical room across from a nurse who is taking notes. I’m at the Red Cross giving blood. The nurse gets excited about my blood because I had been given an anti-malarial without travelling (which is very unusual). I was there for hours too because I remember getting sausage rolls. In 1997 that was a big deal. Normal blood donations usually meant jatz biscuits with some cheese, not the luxury of sausage rolls!

At this stage I still cannot remember what I was given but despair has turned to elation.

Reality kicks in. What did I tell the nurses back in 1997? If I told them what medications I had taken did they note it? Do the notes still exist? How the hell do I access decades old records from the Red Cross?

I make a call to the Red Cross. They explained the process. I email the paperwork in March 2019.

A doctor from the Red Cross returns my call a week later. The news is confirmation of the worst. I was given mefloquine by the Army in March 1997.

I remember screaming into the sand in front of my kids when I heard the news. It was pure RAGE. We had taken the day off to enjoy a swim at a local creek. I had to collect myself before I thanked the doctor. I am so angry I gave my eldest son my phone. It takes me hours to calm down.

* Red Cross records from 1997

I finally calm down.

The evidence was compelling. Not only had I been given mefloquine in 1997 the Army had failed to note it.

Thank goodness for sausage rolls and the Red Cross!

Mefloquine Dispatches: An Index

Stories linked to my experiences after having taken mefloquine as part of my military service.

  1. Mefloquine Dispatches: My Request to Darren Chester
  2. Mefloquine Dispatches: My Daughter, 2016
  3. Mefloquine Dispatches: Raven, 1990s
  4. Mefloquine Dispatches: Harley Quinn, 1997
  5. Mefloquine Dispatches: @NAB, 20th March 2019
  6. Mefloquine Dispatches: @WHO, 8th August 1989
  7. Mefloquine Dispatches: Estadio Nacional Julio Martínez Prádanos, 11th March 2006
  8. Mefloquine Dispatches: Dr Pepper 2.2. 2011 & 1992
  9. Mefloquine Dispatches: The Joker, 1997 & 2019
  10. Mefloquine Dispatches: Acceptance, 2019
  11. Mefloquine Dispatches: Full Bloom, 2012
  12. Mefloquine Dispatches: The Claremont Serial Killings, April 1997
  13. Mefloquine Dispatches: The Commonwealth Department of Veterans Affairs, 2000
  14. Mefloquine Dispatches: SGADF, 26th September 2019
  15. Mefloquine Dispatches: Suicide Prevention, early 1990
  16. Mefloquine Dispatches: Caravaggio, October 2012
  17. Mefloquine Dispatches: FOI, 21st November 2019
  18. Mefloquine Dispatches: Royal Commission, 2020
  19. Mefloquine Dispatches: Lord Dannatt, 28th November 2019
  20. Mefloquine Dispatches: 1800 MEFLOQUINE, 10th May 2019
  21. Mefloquine Dispatches: Mindfulness, 5th December 2019
  22. Mefloquine Dispatches: Mil Mi-24, 27th March 1997
  23. Mefloquine Dispatches: Foreign Affairs, Defence and Trade References Committee, 28th February 2020
  24. Mefloquine Dispatches: Sausage rolls and the Red Cross, 1st July 1997
  25. Mefloquine Dispatches: Mefloquine Dispatches: BUPA, 17th June 2021
  26. Mefloquine Dispatches: LBMC, 28th April 1997
  27. Mefloquine Dispatches: McKinsey & Company, 19th October 2021
  28. Mefloquine Dispatches: 3573 – Lambie, Senator Jacqui, 23rd April 2021